A breathing aid that can help keep coronavirus patients out of intensive care has been created in under a week.
University College London engineers worked with clinicians at UCLH and Mercedes Formula One to build the device, which delivers oxygen to the lungs without needing a ventilator.
Continuous Positive Airway Pressure (CPAP) devices are already used in hospitals but are in short supply.
China and Italy used them to help Covid-19 patients.
Forty of the new devices have been delivered to ULCH and to three other London hospitals. If trials go well, up to 1,000 of the CPAP machines can be produced per day by Mercedes-AMG-HPP, beginning in a week's time.
The Medicines and Healthcare products Regulatory Agency (MHRA) has already given its approval for their use.
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Professor Rebecca Shipley, Director of UCL Institute of Healthcare Engineering, told the BBC: "Normally medical device development would take years but we've done that in days because we went back to a simple existing device and "reverse engineered" it in order to be able to produce them quickly and at scale."
Reverse engineering means they took apart an existing off-patent CPAP device, copied and improved the design and adapted it for mass production.
Early reports from Lombardy in Italy suggest around 50% of patients given CPAP have avoided the need for invasive mechanical ventilation.
UCLH critical care consultant Professor Mervyn Singer said: "These devices are a halfway house between a simple oxygen mask and invasive mechanical ventilation which requires patients to be sedated.
"They will help to save lives by ensuring that ventilators, a limited resource, are used only for the most severely ill."
How does CPAP work?
It pushes a steady flow of air-oxygen mix into the mouth and nose of patients.
This is done at pressure which means the lungs remain open and so it increases the amount of oxygen entering them.
This reduces the effort needed to breathe in, especially when the alveoli – the air sacs in the lungs – have collapsed as a result of Covid-19.
Unlike a simple face mask linked to an oxygen supply, CPAP delivers air and oxygen under pressure, so there needs to be a mask creating a tight seal on the patient's face, over their mouth and nose or a transparent hood over their head.
This is less invasive than a ventilator, for which patients have to be heavily sedated and have a tube inserted into their airway.
But a note of caution was sounded by Duncan Young, Prof of Intensive Care Medicine, University of Oxford, who said: "The use ofRead More – Source
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