The prime minister has admitted his government's plans for easing the coronavirus lockdown are causing "frustration", as he faces a growing revolt from doctors, nurses, teachers and regional councils.
Boris Johnson acknowledged the situation had become more "complex" but said he would trust what he called "the good sense of the British people".
But the mayor of Greater Manchester, Andy Burnham, warned the prime minister of a "fracturing of national unity" if he ignored the concerns of the regions over his roadmap out of the COVID-19 crisis.
Writing in the Mail on Sunday, the prime minister said: "I understand people will feel frustrated with some of the new rules. We are trying to do something that has never had to be done before – moving the country out of a full lockdown, in a way which is safe and does not risk sacrificing all of your hard work.
"I recognise what we are now asking is more complex than simply staying at home, but this is a complex problem and we need to trust in the good sense of the British people."
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It comes as some councils in the regions have said they would support teaching unions in resisting the reopening of schools in England in June.
The devolved administrations in Scotland, Wales and Northern Ireland have refused to follow Mr Johnson's strategy for easing the lockdown, while cities such as Liverpool have said they will not start reopening schools in June as the government wants.
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Talks between teachers' union representatives and government scientific advisers, intended to provide assurance about the government's proposals to enable children to return safely, ended on Friday with union leaders saying it had raised more questions than answers.
Mr Burnham said the prime minister had failed to inform civic leaders of his easing of the lockdown restrictions in advance despite the fact they were the ones who had to deal with demands on the transport system.
The government's change from "stay at home" to "stay alert" advice came as cases of COVID-19 and the virus's reproduction rate – known as the R number – were falling in the South East, but Mr Burnham said he believed it had come too soon for the north.
In an article in The Observer, he warned that without additional support for the regions, there was a danger of a "second spike" in the disease which could then spread again through the Midlands to London.
Mr Burnham said that despite taking part in a call two weeks ago with Mr Johnson and eight other regional mayors, he was given no real notice of the measures announced by the prime minister in his address to the nation last Sunday.
He said: "On the eve of a new working week, the PM was on TV 'actively encouraging' a return to work. Even though that would clearly put more cars on roads and people on trams, no one in government thought it important to tell the cities that would have to cope with that."
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Mr Burnham said the lack of notice was not the only issue Greater Manchester had to deal with.
"The surprisingly permissive package might well be right for the South East, given the fall in caseRead More – Source
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