The 36-year-old has previously spoken out about her difficulties with conceiving, which she discussed at length in the episode.
In the episode, Kardashian spoke about surrogacy, and told her sister, Kim Kardashian, that she had been informed by doctors that if she chose to carry her own second child, it would be a high-risk pregnancy.
On Thursday, Kardashian tweeted as the episode aired and offered her thoughts to those currently going through IVF.
“God bless anyone who is going through the IVF process!” she tweeted.
“That’s definitely not easy. My love is with anyone who is on that journey.”
One person tweeted about the episode and referenced Kardashian’s fertility struggles, writing: “Planning to conceive a child is so emotionally draining and tough when there are so many unknowns. #KUWTK”.
“Amen!!!!!” she wrote. “It’s so so different than my experience with True (obviously) it’s so tough emotionally. Physically it’s not fun but thats short term. Emotionally It can be a struggle.”
Kardashian has been widely praised for speaking out about her fertility struggles, with fans thanking her and sharing their own experiences in response.
“@khloekardashian I can relate to your IVF journey,” tweeted one person.
“I spent the last year going through fertility treatment with all the hormones and it was tough! It ended up successful and now in 19 weeks pregnant. I wish you all the best on your journey!!!”
Another added: “I know you won’t see this but I struggle with fertility too and out of five pregnancies, I’ve had one beautiful little girl from IVF. Watching you go through the hormones and procedures really brings me back and we are about to go for baby #2 also, hang in there!”